Friday, 18 March 2011

AIDS -most dangerous disease

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Acquired Immune Deficiency Syndrome, or AIDS, is a disease of the immune system caused by HIV (Human Immunodeficiency Virus.) AIDS is defined as a syndrome, which means there are a group of health problems that make up this disease. Being infected with HIV progressively reduces the ability of the immune system to fight these infections. Eventually, these viruses, fungi and bacterial infections make a person very ill and at this stage they are said to have AIDS. There is no cure for AIDS, but antiretroviral therapy (ART) can slow down the HIV virus and also slow down damage to the immune system. The group of viruses, bacterial infections and fungi that cause sickness are referred to as opportunistic infections (O Is). Some O Is are very difficult to treat, but newer drugs prevent and treat these infections and work very well. AIDS research and clinical trials are focusing on new therapies, drugs and treatments to prevent or delay the complications of HIV-related disorders.

Although there is no cure for AIDS, the transmission of HIV is preventable. HIV is transmitted through direct contact with bodily fluids, such as blood, semen, vaginal fluid, preseminal fluid and breast milk. Therefore, HIV is contracted by sexual contact, sharing of contaminated hypodermic needles, exchange between mother and baby during pregnancy, breastfeeding or other exchange of body fluids. Prevention is key to controlling the spread of HIV and AIDS. Health organizations promote safe sex (mainly through use of condoms,) and needle exchange programs in attempts to slow the spread of the virus.

The World Health Organization developed a staging system in 1990 for patients infected with HIV, and updated the system in 2005.

Stage I - HIV infection is asymptomatic and not categorized as AIDS.
Stage II- includes minor mucocutaneous manifestations and recurrent upper respiratory tract infections.
Stage III- includes unexplained chronic diarrhea for longer than a month, severe bacterial infections and pulmonary tuberculosis.
Stage IV- includes toxoplasmosis of the brain, candidiasis of the esophagus, trachea, bronchi or lungs and Kaposi's sarcoma; these diseases are indicators of AIDS.

How HIV Spread ??

HOW DOES HIV SPREAD
Infected person’s blood, semen, vaginal fluid are rich in HIV. However tears, saliva, sweat or urine do not pose any danger?
HIV is transmitted by:
  • Unprotected sexual intercourse with infected person (either heterosexual or homosexual)
sexual intercourse with infected malesexual intercourse with infected male result in infection into femalehomosexual intercourse with infected malehomosexual intercourse with infected male result in hiv infection
  • Transfusion of infected blood or blood products
Transfusion of hiv infected blood or blood products
  • Infected mother to her baby during pregnancy, birth process and through breast – feeding
Infected mother to her baby during pregnancy, birth process and through breast  feeding
  • Use of infected needles and instruments without sterilization or sharing of needles and syringes by HIV drug addicts
Use of infected needles result in hiv infection
HOW HIV IS NOT TRANSMITTED
There is no risk of contracting HIV infection in daily routine activities and by casual contact with HIV positive person.
AIDS virus is not transmitted through:
  • Embarrassing or kissing (social)
Embarrassing or kissing (social)
  • Touching hand shaking or hugging
Touching hand shaking or hugging
  • Sharing bathroom or toilet
Sharing bathroom or toilet
  • Coughing, saliva or sneezing
Coughing, saliva or sneezing
  • Eating together or sharing utensils
Eating together or sharing utensils
  • Swimming pools
Swimming pools
  • Sharing clothes
Sharing clothes
  • Mosquito bite, Insect bite or houseflies
Mosquito bite, Insect bite or houseflies
  • Patient caring
Patient caring
Use of infected needles without sterilization result in hiv infection

"AIDS, Difficult to get, Impossible to cure but, Easy to prevent"

How Hiv infect
AIDS is caused by HIV, a very fragile RNA type of retrovirus, which like any other microorganism lives inside the living cells of the body. Outside body it doesn’t survive for more than half and hour.
Human Immunodeficiency Virus - Structure / Structure of aids virus
There are two types of HIV virus, i.e. HIV-1 and HIV-2. HIV-1 is present all over the world and in India more than 80% people are affected by it. HIV-2 is mainly found in Africa and also presents in India. Some people are infected with both the viruses. People only infected with HIV-2 live longer than those infected with HIV-1 and chances of transmission of HIV-2 from mother to child are very rare.
Once in body, HIV attacks CD4 type of White Blood Cells (WBCs) in blood and gradually kills them. 
  Normal Whit Blood Cells protecting our Body   Normal Whit Blood Cells protecting us from infections
These CD4 type of WBC helps us to fight against various infections. 
White Blood Cells and medicines together killing the Infectious agentHIV in our body
Once they are destroyed our body’s resistance to fight infections goes down and person suffers from lots of infections. 
HIV Killing White Blood Cells Infectious agents attacking body in presence of HIV
This end stage of HIV infection is called AIDS. It takes many years for AIDS to develop and till that time infected person usually remains healthy.
Death of a person due to Multiple infections in presence of HIV

Sunday, 13 March 2011

AIDS - The killing diseases

 

 

WHAT DOES “AIDS” MEAN?












AIDS stands for Acquired Immune Deficiency Syndrome:












 Latest AIDS/HIV News


 More AIDS/HIV News



102 has more information on HIV testing.
Being HIV-positive, or having HIV disease, is not the same as having AIDS. Many people are HIV-positive but don’t get sick for many years. As HIV disease continues, it slowly wears down the immune system. Viruses, parasites, fungi and bacteria that usually don’t cause any problems can make you very sick if your immune system is damaged. These are called “opportunistic infections.” See Fact Sheet 500 for an overview of opportunistic infections.



 HOW DO YOU GET AIDS?

 

You don’t actually “get” AIDS. You might get infected with HIV, and later you might develop AIDS. You can get infected with HIV from anyone who’s infected, even if they don’t look sick and even if they haven’t tested HIV-positive yet. The blood, vaginal fluid, semen, and breast milk of people infected with HIV has enough of the virus in it to infect other people. Most people get the HIV virus by:
  • having sex with an infected person
  • sharing a needle (shooting drugs) with someone who’s infected
  • being born when their mother is infected, or drinking the breast milk of an infected woman

Getting a transfusion of infected blood used to be a way people got AIDS, but now the blood supply is screened very carefully and the risk is extremely low.
There are no documented cases of HIV being transmitted by tears or saliva, but it is possible to be infected with HIV through oral sex or in rare cases through deep kissing, especially if you have open sores in your mouth or bleeding gums. For more information, see the following Fact Sheets:


The Centers for Disease Control and Prevention (CDC) estimates that 1 to 1.2 million U.S. residents are living with HIV infection or AIDS; about a quarter of them do not know they have it. About 75 percent of the 40,000 new infections each year are in men, and about 25 percent in women. About half of the new infections are in Blacks, even though they make up only 12 percent of the US population.
In the mid-1990s, AIDS was a leading cause of death. However, newer treatments have cut the AIDS death rate significantly. For more information, see the US Government fact sheet at http://www.niaid.nih.gov/factsheets/aidsstat.htm.



WHAT HAPPENS IF I’M HIV POSITIVE?

You might not know if you get infected by HIV. Some people get fever, headache, sore muscles and joints, stomach ache, swollen lymph glands, or a skin rash for one or two weeks. Most people think it’s the flu. Some people have no symptoms. Fact Sheet 103 has more information on the early stage of HIV infection.
The virus will multiply in your body for a few weeks or even months before your immune system responds. During this time, you won’t test positive for HIV, but you can infect other people.



When your immune system responds, it starts to make antibodies. When this happens, you will test positive for HIV.
After the first flu-like symptoms, some people with HIV stay healthy for ten years or longer. But during this time, HIV is damaging your immune system.
One way to measure the damage to your immune system is to count your CD4 cells you have. These cells, also called “T-helper” cells, are an important part of the immune system. Healthy people have between 500 and 1,500 CD4 cells in a milliliter of blood. Fact Sheet 124 has has more information on CD4 cells.
Without treatment, your CD4 cell count will most likely go down. You might start having signs of HIV disease like fevers, night sweats, diarrhea, or swollen lymph nodes. If you have HIV disease, these problems will last more than a few days, and probably continue for several weeks.


HOW DO I KNOW IF I HAVE AIDS?

HIV disease becomes AIDS when your immune system is seriously damaged. If you have less than 200 CD4 cells or if your CD4 percentage is less than 14%, you have AIDS. See Fact Sheet 124 for more information on CD4 cells. If you get an opportunistic infection, you have AIDS. There is an “official” list of these opportunistic infections put out by the Centers for Disease Control (CDC). The most common ones are:
 


AIDS-related diseases also includes serious weight loss, brain tumors, and other health problems. Without treatment, these opportunistic infections can kill you.
The official (technical) CDC definition of AIDS is available at http://www.cdc.gov/mmwr/preview/mmwrhtml/00018871.htm AIDS is different in every infected person. Some people die a few months after getting infected, while others live fairly normal lives for many years, even after they “officially” have AIDS. A few HIV-positive people stay healthy for many years even without taking antiretroviral medications (ARVs).

IS THERE A CURE FOR AIDS?





There is no cure for AIDS. There are drugs that can slow down the HIV virus, and slow down the damage to your immune system. There is no way to “clear” the HIV out of your body.


The HIV/AIDS situation in different states

 
The vast size of India makes it difficult to examine the effects of HIV on the country as a whole. The majority of states within India have a higher population than most African countries, so a more detailed picture of the crisis can be gained by looking at each state individually.
The HIV prevalence data for most states is established through testing pregnant women at antenatal clinics. While this means that the data are only directly relevant to sexually active women, they still provide a reasonable indication as to the overall HIV prevalence of each area.
The following states have recorded the highest levels of HIV prevalence at antenatal and sexually transmitted disease (STD) clinics over recent years.


Andhra Pradesh

Andhra Pradesh in the southeast of the country has a total population of around 76 million, of whom 6 million live in or around the city of Hyderabad. The HIV prevalence at antenatal clinics was 1% in 2007. This figure is smaller than the reported 1.26% in 2006, but remains the highest out of all states. HIV prevalence at STD clinics was very high at 17% in 2007. Among high-risk groups, HIV prevalence was highest among men who have sex with men (MSM) (17%), followed by female sex workers (9.7%) and IDUs (3.7%).

 

Goa

Goa, a popular tourist destination, is a very small state in the southwest of India (population 1.4 million). In 2007 HIV prevalence among antenatal and STD clinic attendees was 0.18% and 5.6% respectively. The Goa State AIDS Control Society reported that in 2008, a record number of 26,737 people were tested for HIV, of which 1018 (3.81%) tested positive.

Karnataka

Karnataka, a diverse state in the southwest of India, has a population of around 53 million. HIV prevalence among antenatal clinic attendees exceeded 1% from 2003 to 2006, and dropped to 0.5% in 2007. Districts with the highest prevalence tend to be located in and around Bangalore in the southern part of the state, or in northern Karnataka's "devadasi belt". Devadasi women are a group of women who have historically been dedicated to the service of gods. These days, this has evolved into sanctioned prostitution, and as a result many women from this part of the country are supplied to the sex trade in big cities such as Mumbai. The average HIV prevalence among female sex workers in Karnataka was just over 5% in 2007, and 17.6% of men who have sex with men were found to be infected.


Maharashtra

Maharashtra is a very large state of three hundred thousand square kilometres, with a total population of around 97 million. The capital city of Maharashtra - Mumbai (Bombay) - is the most populous city in India, with around 14 million inhabitants. The HIV prevalence at antenatal clinics in Maharashtra was 0.5% in 2007. At 18%, the state has the highest reported rates of HIV prevalence among female sex workers. Similarly high rates were found among injecting drug users (24%) and men who have sex with men (12%).


Tamil Nadu

With a population of over 66 million, Tamil Nadu is the seventh most populous state in India. Between 1995 and 1997 HIV prevalence among pregnant women tripled to around 1.25%. The State Government subsequently set up an AIDS society, which aimed to focus on HIV prevention initiatives. A safe-sex campaign was launched, encouraging condom use and attacking the stigma and ignorance associated with HIV. Between 1996 and 1998 a survey showed that the number of men reporting high-risk sexual behaviour had decreased.


In 2007 HIV prevalence among antenatal clinic attendees was 0.25%. HIV prevalence among injecting drug users was 16.8%, third highest out of all reporting states. HIV prevalence among men who have sex with men and female sex workers was 6.6% and 4.68% respectively.

Manipur

Manipur is a small state of some 2.4 million people in northeast India. Manipur borders Myanmar (Burma), one of the world's largest producers of illicit opium. In the early 1980s drug use became popular in northeast India and it wasn't long before HIV was reported among injecting drug users in the region. Although NACO report a state-wise HIV prevalence of 17.9%  among IDUs, studies from different areas of the state find prevalence to be as high as 32%.


HIV is no longer confined to IDUs, but has spread further to the general population. HIV prevalence at antenatal clinics in Manipur exceeded 1% in recent years, but then declined to 0.75% in 2007. Estimated adult HIV prevalence is the highest out of all states, at 1.57%.

Mizoram

The small northeastern state of Mizoram has fewer than a million inhabitants. In 1998, an HIV epidemic took off quickly among the state's male injecting drug users, with some drug clinics registering HIV rates of more than 70% among their patients. In recent years the average prevalence among this group has been much lower, at around 3-7%. HIV prevalence at antenatal clinics was 0.75% in 2007.


Nagaland

Nagaland is another small northeastern state where injecting drug use has again been the driving force behind the spread of HIV. In 2003 HIV prevalence among IDUs was 8.43%, but has since declined to 1.91% in 2007. HIV prevalence at antenatal clinics and STD clinics was 0.60% and 3.42% respectively in 2007.

          

The Punjab

The Punjab, a state in northern mainland India, has shown an increase in prevalence among injecting drug users (13.8% in 2007) in recent years. One of the richest cities in the Punjab, Ludhiana, has an HIV prevalence of 21% among IDUs while the HIV prevalence among IDUs in the capital of the state, Amritsar, has reached 30%. Denis Broun, head of UNAIDS in India has stated, "the problem of IDUs has been underestimated in mainland India, as most of the problem was thought to be in the northeast."

WHAT DOES “AIDS” MEAN?

 

AIDS stands for Acquired Immune Deficiency Syndrome:
  • Acquired means you can get infected with it;
  • Immune Deficiency means a weakness in the body’s system that fights diseases.
  • Syndrome means a group of health problems that make up a disease.
AIDS is caused by a virus called HIV, the Human Immunodeficiency Virus. If you get infected with HIV, your body will try to fight the infection. It will make “antibodies,” special molecules to fight HIV.
A blood test for HIV looks for these antibodies. If you have them in your blood, it means that you have HIV infection. People who have the HIV antibodies are called “HIV-Positive.” Fact Sheet 102 has more information on HIV testing.
Being HIV-positive, or having HIV disease, is not the same as having AIDS. Many people are HIV-positive but don’t get sick for many years. As HIV disease continues, it slowly wears down the immune system. Viruses, parasites, fungi and bacteria that usually don’t cause any problems can make you very sick if your immune system is damaged. These are called “opportunistic infections.” See Fact Sheet 500 for an overview of opportunistic infections.

HOW DO YOU GET AIDS?

 

 You don’t actually “get” AIDS. You might get infected with HIV, and later you might develop AIDS. You can get infected with HIV from anyone who’s infected, even if they don’t look sick and even if they haven’t tested HIV-positive yet. The blood, vaginal fluid, semen, and breast milk of people infected with HIV has enough of the virus in it to infect other people. Most people get the HIV virus by:

  • having sex with an infected person
  • sharing a needle (shooting drugs) with someone who’s infected
  • being born when their mother is infected, or drinking the breast milk of an infected woman
Getting a transfusion of infected blood used to be a way people got AIDS, but now the blood supply is screened very carefully and the risk is extremely low.
There are no documented cases of HIV being transmitted by tears or saliva, but it is possible to be infected with HIV through oral sex or in rare cases through deep kissing, especially if you have open sores in your mouth or bleeding gums. For more information, see the following Fact Sheets:

What are HIV and AIDS?
Scanning electron microscope image of HIV virons on CD4 lymphocytes.
Electron microscope image of HIV, seen as small spheres on the surface of white blood cells.
HIV is the human immunodeficiency virus. It is the virus that can lead to acquired immune deficiency syndrome, or AIDS. CDC estimates that about 56,000 people in the United States contracted HIV in 2006.
There are two types of HIV, HIV-1 and HIV-2. In the United States, unless otherwise noted, the term “HIV” primarily refers to HIV-1.
Both types of HIV damage a person’s body by destroying specific blood cells, called CD4+ T cells, which are crucial to helping the body fight diseases.
Within a few weeks of being infected with HIV, some people develop flu-like symptoms that last for a week or two, but others have no symptoms at all. People living with HIV may appear and feel healthy for several years. However, even if they feel healthy, HIV is still affecting their bodies. All people with HIV should be seen on a regular basis by a health care provider experienced with treating HIV infection. Many people with HIV, including those who feel healthy, can benefit greatly from current medications used to treat HIV infection. These medications can limit or slow down the destruction of the immune system, improve the health of people living with HIV, and may reduce their ability to transmit HIV. Untreated early HIV infection is also associated with many diseases including cardiovascular disease, kidney disease, liver disease, and cancer.  Support services are also available to many people with HIV. These services can help people cope with their diagnosis, reduce risk behavior, and find needed services.
AIDS is the late stage of HIV infection, when a person’s immune system is severely damaged and has difficulty fighting diseases and certain cancers. Before the development of certain medications, people with HIV could progress to AIDS in just a few years. Currently, people can live much longer - even decades - with HIV before they develop AIDS. This is because of “highly active” combinations of medications that were introduced in the mid 1990s.







HIV Testing 101




January 4, 2010

Is It a Risk? How risky are certain activities? Pick one from the pulldown menu or click here and find out!

There's only one way to find out for sure whether you have HIV: Get tested. Although some people feel symptoms when they've been newly infected with HIV, most people don't. That's one reason why HIV continues to spread throughout the world: Millions of people are estimated to be living with HIV without even knowing it. That's why it's so important for everybody to get tested regularly for HIV, if they have sex or use injection drugs.
It's completely normal to get nervous, scared or even a little paranoid when you think you've put yourself at risk for HIV. An HIV test -- taken at least six weeks after the risky event -- can answer that question. Approved HIV tests are extremely reliable. There's even a saliva test you can take at many doctor's offices or clinics that will give you results in less than half an hour. (If it comes out positive, you'll need to get an even more reliable blood test, known as a Western Blot, that will confirm the results in a couple of weeks.) And don't forget, if you are at risk for HIV from sex, then you are also at risk for other sexually transmitted diseases that can be much easier to get.
If you live in the United States and are concerned about your privacy, in much of the United States, especially in cities, there are clinics and hospitals where you can be tested for HIV completely anonymously. There are even places that will help you notify past partners if you do test positive for HIV.